The phenomenon of irregular growth of some parts of the body has a name, “overgrowth” syndrome. This finding was achieved by researchers who studied capillary malformations at the fingertips.
Researchers in Spain have discovered what they called the “overgrowth syndrome,” a rare disease that causes irregular growth and some malformations in certain parts of the body. The finding came in the wake of the study “Capillary Malformations at the Fingertips and Associated Disorders: A 9-Case Report”, published in the journal Pediatrics of the American Academy of Pediatrics.
This syndrome is revealed by a “hyper growth”, that is, a very abnormal increase of some parts of the body. In some cases, these abnormalities arise at birth. After this “abnormal growth,” the researchers highlighted the so-called Finca syndrome (which occurs when overgrowth affects the fingertips centripetally). This discovery was made by specialists from the University Hospital La Paz, in Madrid, and from the University Clinic of Navarra.
All capillary malformations represent the most frequent vascular anomalies. Although often considered as isolated cases, they may present many other more serious deformations.
Speaking of Finca syndrome (the anomaly at the fingertips), the minors to whom the disease was diagnosed, had very serious problems, said Juan Carlos López-Gutiérrez, the main responsible for the study and also for the area of Congenital Vascular Anomalies of the department Of La Paz Pediatric Surgery. The researcher, quoted by El Mundo, said that these problems were found over the course of nine years and that “all patients ended up with problems of pulmonary thromboembolism or neurological disorders caused by coagulation problems”.
“So far, we have not found any patients with capillary malformation at the fingertips who have no other malformations associated”, he added.
Thus, this finding will allow us to look for other genes that relate the overgrowth to other vascular anomalies. The first step, researchers believe, is to be able to study the tissues of patients with this anomaly.
“We expect to find these fabrics within five years”, he said.
During nine years (between 2006 and 2016) nine patients were diagnosed and in all of them the anomalies were found as soon as they were born.