It was a team of US researchers, who concluded that lowering the level of glucose in the brain, stimulates Alzheimer’s symptoms, thus proposing a way to fight the disease.
The direct link between low levels of glucose in the brain and Alzheimer’s was already known to the scientific community and physicians, but it was a team of researchers at Temple University in the United States who recently discovered that this link may be even deeper Than what was known.
Now in a study published in the journal Translational Psychiatry, the team led by researcher Domenico Praticò reveals that he found that lowering glucose levels occurs long before the first symptoms of the disease (memory loss and cognitive difficulties) and may even motivate the Symptoms. In addition, the researchers report in this article, a treatment that can prevent the fall in glucose levels, which may ultimately mean the prevention of Alzheimer’s.
These experts identified new evidence pointing to a notion that was already known, the involvement of p38 protein in this process. According to Domenico Praticò, “there is now much evidence that p38 protein is involved in the development of Alzheimer’s disease”. Thus, they propose the use of this protein in the production of a medicament for the possibility of preventing the disease.
This study was performed using laboratory mice, the researchers reduced the glucose level in the brains of the animals and observed the result of this experiment. What has happened is that mice that have been slowed down to glucose levels have suffered a decline in brain cell function, have failed far more in memory tests, and have yet to accelerate cell death in the brain. These are symptoms that indicate the onset of Alzheimer’s disease.